
Nano Hydroxyapatite Toothpaste
Formulate and manufacture premium fluoride-free toothpaste with nano hydroxyapatite to strengthen enamel, support sensitive teeth, and prevent plaque buildup. Build your brand with science-backed ingredients.
A Safe & Effective Alternative to Fluoride
Approximately 97% of tooth enamel is made of a naturally occurring mineral called hydroxyapatite (a combination of mainly calcium and phosphorus). NASA first synthesized a biocompatible version called nano hydroxyapatite (nHA) to help bone and tooth density loss in zero gravity experienced by astronauts.
We formulate private label toothpastes using tiny particles of hydroxyapatite that easily bind to enamel. This helps to fill in microfissures and cracks while remineralizing and strengthening the teeth.
The nHA we use can also be formulated to occlude dentin tubules and provide support for sensitive teeth without the use of nerve-numbing drugs. And, by making the surface smoother, nHA helps to inhibit bacteria and plaque from clinging to teeth.

See the Remineralization
Nano hydroxyapatite particles are small enough to penetrate and fill microscopic fissures in the enamel, restoring the surface and providing relief from sensitivity.


Naturally Sourced & Derived Ingredients
We combine nano hydroxyapatite with synergistic, naturally derived ingredients that work together to provide high-performance formulas you can count on.
Enamel Protection
Formulations featuring baking soda to support oral health by neutralizing acids caused by harmful bacteria.
Whitening & Polishing
Incorporate ultra-fine micro abrasives from naturally occurring sources like calcium carbonate and hydrated silica.
Custom Flavoring
Xylitol to boost salivation, combined with premium essential oils to give your toothpaste appealing flavors and leave breath fresh.
Private Label Oral Care Formulas & Types
Expand your oral care catalog beyond basic mint paste. From classic enamel-repair nHA formulas to next-generation bioactive peptide toothpastes, we manufacture high-performance oral care for every niche.

Advanced Peptide + nHA Toothpaste
Inspired by high-end skincare innovation (like PeptiSmile™), this dual-action formula pairs nano hydroxyapatite for mineral enamel repair with bioactive peptides (Palmitoyl Tetrapeptide-7) for targeted gumline and mucosal soft-tissue resilience.
Palmitoyl Tetrapeptide-7
Skincare-grade peptides adapted for oral soft tissue matrix support & gumline protection.
Tranexamic Acid + Xylitol
Calms soft tissue redness, regulates pH, and leaves a clean, silky polished mouthfeel.
Dipotassium Glycyrrhizinate
Licorice root extract derivative that soothes sensitive gums and soft oral tissues.
Vitamin E (Tocopherol)
Antioxidant defense against oral oxidative stress with superior stability.
We Have Formulas For All Smiles
Whether you are targeting the sensitive teeth market, cosmetic whitening, bio-hacking oral care, or children's fluoride-free toothpaste, we can manufacture your exact specification.
Advanced Peptide + Mucosal Care
Incorporates Palmitoyl Tetrapeptide-7, Tranexamic Acid, and Licorice derivatives for soft-tissue and gumline nutrition alongside enamel repair.
Sensitive + Enamel Repair (Classic nHA)
An excellent everyday fluoride-free option that seals dentin tubules and strengthens tooth enamel naturally.
Extra Whitening & Polishing
Combines nHA with gentle hydrated silica, baking soda, or papain enzymes for bright stain removal without peroxide erosion.
Clean, Vegan & Eco-Packaged
Sulfate-free (SLS-free), paraben-free, cruelty-free formulas packaged in recyclable aluminum or bio-PE tubes.
Design Your Exact Specification
Pick your active tier, peptide concentration, flavor, boosters, and packaging — then request a custom batch sample in one click.
Build Your Custom Oral Care Formula
Select your active levels, peptide concentration, flavor profile, and functional boosters. Your configuration carries directly into the sample request — no back-and-forth needed.
Active Tier
Peptide Concentration
(Palmitoyl Tetrapeptide-7)Light peptide load for everyday gumline support alongside enamel care.
Flavor Profile
Functional Boosters
(optional, multi-select)Packaging / Tube Size
Your Formula Summary
Frequently Asked Questions
Ready to Launch Your Oral Care Line?
Contact us to discuss your custom nano hydroxyapatite formulation.
Get a Free Quote
Fill out the form below and our team will get back to you within 24 hours.
Ready to build or scale your product?
We take you from concept to shelf — custom formulation, low-MOQ manufacturing, and packaging under one roof. No pressure; if we are not the right fit, we will tell you.

